Steffimycin B
Steffimycin B is an anthracycline bacterial metabolite originally isolated from Streptomyces. It binds to DNA, preferentially intercalating at sites containing cytosine and guanine.2 Steffimycin B is cytotoxic to MCF-7, KB, NCI-H187, and Vero cells (IC50s=3.5, 6.75, 3.28, and 10.5 μM, respectively). It is active against M. tuberculosis (MIC=5.2 nM), B. cereus (MIC=1.56 μg/mL), and P. falciparum (IC50=2.19 μM).
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 54526-94-2
- Formel: C29H32O13
- Molecular Weight:588.56
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biologische Aktivität
-
Chemical Information
- Reinheit & Dokumentation
- Verweise
-
Help & FAQs
-
HY-B0223S2
Albendazole-d7
-
HY-111939
Amiprofos methyl
-
HY-138149
2-epi-Abamectin
-
HY-N0402S
Artemether-d3
-
HY-124452
Nocardamine
-
HY-N8383
Butyrolactone V
-
HY-N7536
Voacangine
-
HY-113784
Thiocarlide
-
HY-N12231
Carbazomycin B
-
HY-111939R
Amiprofos methyl (Standard)
-
HY-Z8143
3-Keto fusidic acid
-
HY-N10255
Trypacidin
Biologische Aktivität
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
2.8 μM
Compound: 9
|
Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by alamar blue assay
Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by alamar blue assay
|
[PMID: 38412432] |
| PC-3 | IC50 |
3.1 μM
Compound: 9
|
Cytotoxicity against human PC-3 cells assessed as reduction in cell viability incubated for 72 hrs by alamar blue assay
Cytotoxicity against human PC-3 cells assessed as reduction in cell viability incubated for 72 hrs by alamar blue assay
|
[PMID: 38412432] |
Chemical Information
-
CAS. Nr. 54526-94-2
-
Molecular Weight 588.56
-
Formel C29H32O13
-
SMILES
OC1=C(C(C2=C3O)=O)C(C(C2=CC(OC)=C3)=O)=CC(C4=O)=C1[C@H]([C@@H]([C@](O)4C)OC)O[C@H](O[C@H]5C)[C@@H]([C@@H]([C@H]5OC)O)OC
-
Synonyms
NSC 204855; U 40615
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Steffimycin B Related Classifications
HY-N8470 Related Classifications
Powered by Bioz