Thalidomide-S-COOH
Thalidomide-S-COOH is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 2378582-26-2
- Formel: C15H12N2O6S
- Molecular Weight:348.33
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Alle E3 Ligase Ligand-Linker Conjugates Isoform-spezifische Produkte anzeigen
More
Biologische Aktivität
Beschreibung
IC50 & Target
|
Cereblon |
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS. Nr. 2378582-26-2
-
Molecular Weight 348.33
-
Formel C15H12N2O6S
-
SMILES
O=C(O)CSC1=CC=CC=2C(=O)N(C(=O)C12)C3C(=O)NC(=O)CC3
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)