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Art. -Nr.: HY-183886

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U 80493

U 80493 is a HIV-1 reverse transcriptase inhibitor with IC₅₀ of 20 μM. U 80493 can be used for the research of acquired immunodeficiency syndrome.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

CAS. Nr.: 136816-67-6
Formel: C₂₁H₃₀N₄O
Molecular Weight:354.49

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

U 80493 Chemical Structure

CAS. Nr.: 136816-67-6

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

U 80493 is a HIV-1 reverse transcriptase inhibitor with IC₅₀ of 20 μM. U 80493 can be used for the research of acquired immunodeficiency syndrome^[1].

IC₅₀ & Target^[1]

HIV-1

20 μM (IC₅₀)

Alle HIV Isoform-spezifische Produkte anzeigen :

In Vitro

U 80493 (Compound 8) inhibits HIV-1 IIIb replication in MT-2 cells with an ED₅₀ of 2 μM and has a CC₅₀ of 15 μM^[1].
U 80493 inhibits HIV-1 D34 replication in PBMC with an ED₅₀ of 1-10 μM and has a CC₅₀ greater than 10 μM^[1].
U 80493 inhibits HIV-1 IIIb replication in H9 cells with an ED₅₀ of 1 μM and has a CC₅₀ of 10 μM^[1].
U 80493 inhibits recombinant HIV-1 RT activity with an IC₅₀ of 20 μM^[1].
U 80493 (100 μM) inhibits recombinant HIV-1 RT activity by 73%^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 136816-67-6
Molecular Weight 354.49
Formel C₂₁H₃₀N₄O
SMILES

CCNC1=CC=CN=C1N2CCN(CC2)CC3=CC(C)=C(OC)C(C)=C3
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Xu H, et al. Progress of bis(heteroaryl)piperazines (BHAPs) as non-nucleoside reverse transcriptase inhibitors (NNRTIs) against human immunodeficiency virus type 1 (HIV-1). Mini Rev Med Chem. 2010;10(1):62-72. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise

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U 80493

Alle HIV Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

U 80493 Related Classifications

HY-183886 Related Classifications