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Art. -Nr.: HY-117291

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XMD-17-51

Name: XMD-17-51
Brand: MedChemExpress
SKU: HY-117291
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1 Cited Publications

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XMD-17-51 is a pyrimido-diazepinone compound that is able to modulate protein kinases.

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CAS. Nr.: 1628614-50-5
Formel: C₂₁H₂₄N₈O
Molecular Weight:404.47

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

XMD-17-51 Chemical Structure

CAS. Nr.: 1628614-50-5

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
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- In Vitro
Chemical Information
Publications (1)
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Biologische Aktivität

Beschreibung

XMD-17-51 is a pyrimido-diazepinone compound that is able to modulate protein kinases^[1].

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In Vitro

XMD-17-51 is a pyrimido-diazepinone compound that is able to modulate protein kinases, including MPS1 (TTK), ERK5 (BMK1, MAPK7), polo kinase 1, 2, 3, or 4, Ack1, Ack2, Abl, DCAMKL1, ABL1, Abl mutants, DCAMKL2, ARK5, BRK, MKNK2, FGFR4, TNK1, PLK, ULK2, PLK, PRKD1, PRKD2, PRKD3, ROS1, RPS6KA6, TAOK1, TAOK3, TNK2, Bcr-Abl, GAK, cSrc, TPR-Met, Tie2, MET, FGFR3, Aurora, Axl, Bmx, BTK, c-kit, CHK2, Flt3, MST2, p70S6K, PDGFR, PKB, PKC, Raf, ROCK-H, Rsk1, SGK, TrkA, TrkB and TrkC, and can be used in the treatment of various diseases, disorders or conditions^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 1628614-50-5
Molecular Weight 404.47
Formel C₂₁H₂₄N₈O
SMILES

O=C1N(C)C2=CN=C(NC3=CN(C4CCNCC4)N=C3)N=C2N(C)C5=CC=CC=C15
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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Front Pharmacol

XMD-17-51 Inhibits DCLK1 Kinase and Prevents Lung Cancer Progression. [Abstract]

2021 Mar 8:12:603453. PMID: 33762936

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. WO 2014145909 A2.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Keywords

XMD-17-51

1 Cited Publications

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Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Publications (1)
Reinheit & Dokumentation
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XMD-17-51

Publications Citing Use of MedChemExpress (MCE) XMD-17-51

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