Beiwutine
Based on 1 Customer Validation
Beiwutine (10-Hydroxy mesaconitine) is a diester diterpenoid alkaloid.
For research use only. We do not sell to patients.
- Purity: 98.94%
- CAS No.: 76918-93-9
- Formula: C33H45NO12
- Molecular Weight:647.71
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Bioactive Compound Library Max
HY-L181
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Bioactive Compound Library
HY-L001
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Natural Product Library
HY-L021
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Medicine Food Homology Compound Library
HY-L055
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Terpenoids Library
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Traditional Chinese Medicine Active Compound Library
HY-L065
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Alkaloids Library
HY-L071
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Plant-Sourced Natural Product Library
HY-L115
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Heterocyclic Compound Library
HY-L138
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MCE Bioactive Compound Library
HY-L001V
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Natural Product Library Plus
HY-L021P
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Natural Product and Natural Product-Like Compound Library
HY-L021M
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Heat-Clearing and Detoxification Traditional Chinese Medicine Compound Library
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High-Throughput Bioactive Compound Library
HY-L205
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High-Throughput Natural Product Library
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Ancient Chinese Classical Formulas Traditional Chinese Medicine Active Compound Library
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Diarrhea-Related Traditional Chinese Medicine Active Compound Library
HY-L224
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Mongolian Medicine Compound Library
HY-L238
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Natural Product Diversity Scaffold Library
HY-L245
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Mass Spectrometry Natural Product Library
HY-L262
Biological Activity
Chemical Information
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CAS No. 76918-93-9
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Appearance Solid
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Molecular Weight 647.71
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Formula C33H45NO12
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Color White to off-white
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SMILES
O[C@]([C@H](C1([H])OC(C2=CC=CC=C2)=O)[C@@]3([C@H]4O)OC(C)=O)(C[C@@]1([C@H]4OC)O)C(C(N5C)C3[C@@H]6OC)([C@H](C[C@H]7O)OC)[C@@]6([H])[C@@]7(C5)COC
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Synonyms
10-Hydroxy mesaconitine
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 100 mg/mL (154.39 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (3.86 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (3.86 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL. * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (283 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 1.5439 mL | 7.7195 mL | 15.4390 mL | 38.5975 mL |
| 5 mM | 0.3088 mL | 1.5439 mL | 3.0878 mL | 7.7195 mL | |
| 10 mM | 0.1544 mL | 0.7720 mL | 1.5439 mL | 3.8598 mL | |
| 15 mM | 0.1029 mL | 0.5146 mL | 1.0293 mL | 2.5732 mL | |
| 20 mM | 0.0772 mL | 0.3860 mL | 0.7720 mL | 1.9299 mL | |
| 25 mM | 0.0618 mL | 0.3088 mL | 0.6176 mL | 1.5439 mL | |
| 30 mM | 0.0515 mL | 0.2573 mL | 0.5146 mL | 1.2866 mL | |
| 40 mM | 0.0386 mL | 0.1930 mL | 0.3860 mL | 0.9649 mL | |
| 50 mM | 0.0309 mL | 0.1544 mL | 0.3088 mL | 0.7720 mL | |
| 60 mM | 0.0257 mL | 0.1287 mL | 0.2573 mL | 0.6433 mL | |
| 80 mM | 0.0193 mL | 0.0965 mL | 0.1930 mL | 0.4825 mL | |
| 100 mM | 0.0154 mL | 0.0772 mL | 0.1544 mL | 0.3860 mL |
Beiwutine Related Classifications
HY-N7608 Related Classifications
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