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Lactic acid potassium

(Synonyms: DL-Lactic acid potassium; E-270 potassium)
63 Cited Publications
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Based on 63 publication(s) in Google Scholar

Lactic acid (DL-Lactic acid) potassium is a hydroxycarboxylic acid receptor 1 (HCAR1) activator and an epigenetic modulator inducing lysine residues lactylation. Lactic acid potassium is a glycolysis end-product, bridging the gap between glycolysis and oxidative phosphorylation. Lactic acid potassium is an oncometabolite and has immune protective role of lactate in anti-tumor immunity. Lactic acid also potassium has antimicrobial activity, which can be used as a food preservative.

For research use only. We do not sell to patients.

  • Purity: 60.8%
  • CAS No.: 996-31-6
  • Formula: C3H5KO3
  • Molecular Weight:128.17
  • Storage:

    4°C, sealed storage, away from moisture

    * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

  • Lactic acid potassium Chemical Structure
    Lactic acid potassium Chemical Structure
  • Experimental Validation Results for Lactic acid potassium
  • Experimental Validation Results for Lactic acid potassium
  • Experimental Validation Results for Lactic acid potassium
  • Experimental Validation Results for Lactic acid potassium
  • Experimental Validation Results for Lactic acid potassium
  • Experimental Validation Results for Lactic acid potassium
  • Experimental Validation Results for Lactic acid potassium
  • Experimental Validation Results for Lactic acid potassium
  • Experimental Validation Results for Lactic acid potassium
CAS No.: 996-31-6
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WBIPIFRT-PCR
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  • IF
  • RT-PCR
  • IP
  • WB
  • IP
  • RT-PCR

All Endogenous Metabolite Isoforms

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All Hydroxycarboxylic Acid Receptor (HCAR) Isoforms

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  • Lactic acid potassium Chemical Structure
    Lactic acid potassium Chemical Structure
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    Lactic acid potassium purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Jul 29:e09477. [Abstract]

    Customer Validation
     Following the direct addition of lactic acid (a final concentration of 100 mM) to the culture medium for 12 h, western blotting, and immunoprecipitation assays revealed a significant increase in the total lactylation and corresponding lysine-312 lactylation levels in ASH2L

  • 1/16

    Lactic acid potassium purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Mar 27:e2413709. [Abstract]

    Customer Validation
     Western blot of UGDH lactylation in chondrocytes with Lactic acid sodium (lactate) (25 mM) treatment for 24 h.

  • 1/16

    Lactic acid potassium purchased from MedChemExpress. Usage Cited in: Redox Biol. 2025 Apr:81:103553. [Abstract]

    Customer Validation
     Immunoblot and quantification analyses of NFS1 in HCC cells incubated with 0, 5, or 10 mM lactate after being subjected to either a 47 °C or 37 °C water bath.

  • 1/16

    Lactic acid potassium purchased from MedChemExpress. Usage Cited in: Cell Death Dis. 2025 Mar 20;16(1):193. [Abstract]

    Customer Validation
     Lactate sodium (5-15 mM; 24 h) ​​results​​ in increased H4K12la (red) levels in CCSCs compared to the control group.

  • 1/16

    Lactic acid potassium purchased from MedChemExpress. Usage Cited in: Cell Death Dis. 2025 Feb 28;16(1):144. [Abstract]

    Customer Validation
     Lactate (25 mM) significantly increases the mRNA and protein expression of FBXO33.

  • 1/16

    Lactic acid potassium purchased from MedChemExpress. Usage Cited in: Cell Death Dis. 2025 Feb 28;16(1):144. [Abstract]

    Customer Validation
     Co-IP detected the effect of lactate on YY1 protein lactylation modification.

  • 1/16

    Lactic acid potassium purchased from MedChemExpress. Usage Cited in: J Exp Clin Cancer Res. 2024 Mar 5;43(1):68. [Abstract]

    Customer Validation
     Lactate sodium increases IGF-1R levels in PI-resistant KAS-6/1 and U266 cells.

  • 1/16

    Lactic acid potassium purchased from MedChemExpress. Usage Cited in: Cell Res. 2023 Sep;33(9):679-698. [Abstract]

    Customer Validation
     Lactate (NALA) (300 mM; 24 h) significantly upregulates α-MHC K1897 lactylation in H9c2 cells.

  • 1/16

    Lactic acid potassium purchased from MedChemExpress. Usage Cited in: J Ginseng Res. 2024 May;48(3):298-309. [Abstract]

    Customer Validation
     The expression level of METTL3, YTHDF1, YTHDF2, and YTHDC1 in NB4-R1 and NB4-R2 cells treated with 20 μM oxamate or 20 μM lactate or 1 μM ATRA for 48 h was detected via qRT-PCR.

  • Lactic acid potassium