MES potassium
Based on 4 publication(s) in Google Scholar
MES (2-Morpholinoethanesulphonic acid) potassium is a kind of amphoteric ion buffer, the buffer capacity ranging pH 5.5-7.0. As a Good's buffer, MES potassium is widely used in biochemistry and molecular biology experiments, such as cell culture, enzyme activity determination, electrophoresis and protein studies.
For research use only. We do not sell to patients.
- Purity: 99.88%
- CAS No.: 39946-25-3
- Formula: C6H12KNO4S
- Molecular Weight:233.33
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Storage:
RT, sealed storage, away from moisture and light.
In solvent -80°C, 1 year , -20°C, 6 months
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) MES potassium
More
Biological Activity
MES potassium is a zwitterionic buffer and can provide effective buffering capacity at around pH 6.15. The pKa value of MES potassium changes with temperature, so the change of its pKa value needs to be considered when using it at different temperatures[1].
MES potassium shows good buffering properties in biological experiments, exhibits poor affinity with metal ions (binding constants at 20 °C and 0.1 M: Mg2+, 0.8; Ca2+, 0.8; Mn2+, 1.7), thereby can be used in studies involving metal ions[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 39946-25-3
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Appearance Solid
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Molecular Weight 233.33
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Formula C6H12KNO4S
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Color White to off-white
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SMILES
O=S(CCN1CCOCC1)(O[K])=O
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Synonyms
2-Morpholinoethanesulphonic acid potassium
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
RT, sealed storage, away from moisture and light
In solvent -80°C 1 year -20°C 6 months
Publications (4)
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Journal Impact Factor
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Most Recent
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J Nanobiotechnology
A novel spherical GelMA-HAMA hydrogel encapsulating APET×2 polypeptide and CFIm25-targeting sgRNA for immune microenvironment modulation and nucleus pulposus regeneration in intervertebral discs. [Abstract]2024 Sep 12;22(1):556. PMID: 39267105 -
Phytomedicine
Da-Bu-Yin-Wan rescues cognitive deficits in aging and Alzheimer's disease models by Wnt/β-catenin-dependent restoration of lysosomal acidification. [Abstract]2026 Apr:153:157916. PMID: 41662806 -
J Colloid Interface Sci
Enhanced photostability and targeting ability of hollow mesoporous manganese-based nanocarriers for NIR-II fluorescence image-guided surgery and photothermal therapy. [Abstract]2025 Nov 15:698:138094. PMID: 40494115 -
Cell Biol Toxicol
IGFBP3 enhances adipose-derived stem cell function in soft tissue injury repair via ITGB1 and ERK pathway activation. [Abstract]2025 May 15;41(1):85. PMID: 40369223
Solvent & Solubility
H2O : 100 mg/mL (428.58 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
[1]. N E Good, et al. Hydrogen ion buffers for biological research. Biochemistry. 1966 Feb;5(2):467-77. [Content Brief]
[2]. Tomoko Kagenishi, et al. MES Buffer Affects Arabidopsis Root Apex Zonation and Root Growth by Suppressing Superoxide Generation in Root Apex. Front Plant Sci. 2016 Feb 18;7:79. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 4.2858 mL | 21.4289 mL | 42.8578 mL | 107.1444 mL |
| 5 mM | 0.8572 mL | 4.2858 mL | 8.5716 mL | 21.4289 mL | |
| 10 mM | 0.4286 mL | 2.1429 mL | 4.2858 mL | 10.7144 mL | |
| 15 mM | 0.2857 mL | 1.4286 mL | 2.8572 mL | 7.1430 mL | |
| 20 mM | 0.2143 mL | 1.0714 mL | 2.1429 mL | 5.3572 mL | |
| 25 mM | 0.1714 mL | 0.8572 mL | 1.7143 mL | 4.2858 mL | |
| 30 mM | 0.1429 mL | 0.7143 mL | 1.4286 mL | 3.5715 mL | |
| 40 mM | 0.1071 mL | 0.5357 mL | 1.0714 mL | 2.6786 mL | |
| 50 mM | 0.0857 mL | 0.4286 mL | 0.8572 mL | 2.1429 mL | |
| 60 mM | 0.0714 mL | 0.3571 mL | 0.7143 mL | 1.7857 mL | |
| 80 mM | 0.0536 mL | 0.2679 mL | 0.5357 mL | 1.3393 mL | |
| 100 mM | 0.0429 mL | 0.2143 mL | 0.4286 mL | 1.0714 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
MES potassium Related Classifications
HY-D0858E Related Classifications
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