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NNRT-IN-4

NNRT-IN-4 (Compound 10p) is an inhibitor for non-nucleoside reverse transcriptase (NNRT) with an IC50 of 0.713 µM for HIV-1 RT. NNRT-IN-4 exhibits antiviral efficacy, inhibits HIV-1 wildtype and mutant strains with EC50 of 6-63 nM. NNRT-IN-4 exhibits a slight inhibitory activities against hERG (IC50=25.9 µM) and CYP enzymes (IC50>50 µM). NNRT-IN-4 exhibits good tolerability and safety in mice (2 g/kg).

For research use only. We do not sell to patients.

  • Formula: C36H38N6O4
  • Molecular Weight:618.72
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • NNRT-IN-4 Chemical Structure
    NNRT-IN-4 Chemical Structure
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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Use of MCE Products

All HIV Isoforms

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  • NNRT-IN-4 Chemical Structure
    NNRT-IN-4 Chemical Structure
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  • NNRT-IN-4