RSK
The p90 ribosomal protein S6 kinases RSK1 through RSK4 (RPS6KA1-6, MAPKAP-K1) are terminal effectors of the ERK1/2 MAPK cascade and possess a unique tandem-kinase architecture. The C-terminal kinase domain is phosphorylated by ERK, then intramolecularly activates the N-terminal kinase domain, while PDK1 also phosphorylates the NTKD activation loop, integrating growth-factor and MAPK inputs. Active RSKs phosphorylate CREB, c-Fos, ribosomal protein S6, BAD, and p27Kip1, driving immediate-early gene induction, protein synthesis, and survival. RSK2 loss-of-function mutations cause Coffin-Lowry syndrome, an X-linked intellectual disability with skeletal defects, and RSK activity contributes to proliferation and therapy resistance in cancers downstream of oncogenic RAS and FGFR signaling, making the RSK branch an active oncology target.
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RSK Recombinant Proteins (16)
S6K1/RPS6KB1 Protein, Human (Inactive, sf9, GST)
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Cat. No.: HY-P76588
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: RPS6KB1; Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1; Prev. STK14A; 70 KDa Ribosomal Protein S6 Kinase 1; S6K1; Serine/Threonine Kinase 14 Alpha; P70(S6K)-Alpha; P70 Ribosomal S6 Kinase Alpha; PS6K; P70 S6 Kinase Alpha; S6K; RPS6KB1 Protein; Serine/
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MSK1 Protein, Human (Active, sf9, GST)
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Cat. No.: HY-P701819
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: RPS6KA5; RSK-Like Protein Kinase; Ribosomal Protein S6 Kinase A5; S6K-Alpha-5; MSK1; RSKL; RLPK; Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5; Nuclear Mitogen- And Stress-Activated Protein Kinase 1; Ribosomal Protein S6 Kinase, 90kD, Polypeptide 5; 9
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RSK1 Protein, Human (sf9, His)
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Cat. No.: HY-P701772
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: RPS6KA1; MAPKAPK1A; Ribosomal Protein S6 Kinase A1; P90-RSK 1; RSK1; P90RSK1; MAPKAPK1; P90S6K; P90Rsk; RSK-1; HU-1; DJ590P13.1 (Ribosomal Protein S6 Kinase, 90kD, Polypeptide 1); MAP Kinase-Activated Protein Kinase 1a; Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1; 90 KDa Ribosomal Protein S6 Kinase 1; Ribosomal Protein S6 Kinase, 90kD, Polypeptide 1; Ribosomal Protein S6 Kinase Alpha-1; Ribosomal Protein S6 Kinase; MAPK-Activated Protein Kinase 1a; S6K-Alpha 1; Ribosomal S6 Kinase 1; S6K-Alpha-1; MAPKAP Kinase 1a; RSK; MAPKAPK-1a
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S6K1/RPS6KB1 Protein, Human (Active, 421a.a, T412E, sf9, His-GST)
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Cat. No.: HY-P706097
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: RPS6KB1; Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1; Prev. STK14A; 70 KDa Ribosomal Protein S6 Kinase 1; S6K1; Serine/Threonine Kinase 14 Alpha; P70(S6K)-Alpha; P70 Ribosomal S6 Kinase Alpha; PS6K; P70 S6 Kinase Alpha; S6K; RPS6KB1 Protein; Serine/Threonine-Protein Kinase 14A; P70 S6K-Alpha; Ribosomal Protein S6 Kinase Beta-1; P70-Alpha; Ribosomal Protein S6 Kinase I; P70-S6K 1; S6K-Beta-1; P70-S6K; P70 S6KA; P70S6K1; Ribosomal Protein S6 Kinase B1; Ribosomal Protein S6 Kinase, 70kD, Polypeptide 1
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RSK3 Protein, Human (Active, sf9, GST)
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Cat. No.: HY-P76011
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: RPS6KA2; Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 2; Ribosomal Protein S6 Kinase A2; Ribosomal Protein S6 Kinase, 90kD, Polypeptide 2; RSK3; Non-Specific Serine/Threonine Protein Kinase; HU-2; 90 KDa Ribosomal Protein S6 Kinase 2; MAP Kinase-Activa
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RSK1 Protein, Human (sf9)
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Cat. No.: HY-P701771
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: RPS6KA1; MAPKAPK1A; Ribosomal Protein S6 Kinase A1; P90-RSK 1; RSK1; P90RSK1; MAPKAPK1; P90S6K; P90Rsk; RSK-1; HU-1; DJ590P13.1 (Ribosomal Protein S6 Kinase, 90kD, Polypeptide 1); MAP Kinase-Activated Protein Kinase 1a; Ribosomal Protein S6 Kinase, 90kDa,
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RSK2 Protein, Human
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Cat. No.: HY-P701773
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: RPS6KA3; Pp90RSK2; Prev. MRX19; RSK-2; Prev. CLS; Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3; RSK2; Ribosomal Protein S6 Kinase, 90kD, Polypeptide 3; Insulin-Stimulated Protein Kinase 1; Non-Specific Serine/Threonine Protein Kinase; HU-3; Epididymi
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RSK2 Protein, Human (His)
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Cat. No.: HY-P701774
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: RPS6KA3; Pp90RSK2; Prev. MRX19; RSK-2; Prev. CLS; Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3; RSK2; Ribosomal Protein S6 Kinase, 90kD, Polypeptide 3; Insulin-Stimulated Protein Kinase 1; Non-Specific Serine/Threonine Protein Kinase; HU-3; Epididymi
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RPS6KA4 Protein, Human (Active, sf9, His, GST)
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Cat. No.: HY-P702650
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: RPS6KA4; S6K-Alpha-4; Ribosomal Protein S6 Kinase A4; Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 4; MSK2; Ribosomal Protein S6 Kinase, 90kD, Polypeptide 4; RSK-B; Mitogen- And Stress-Activated Protein Kinase 2; Nuclear Mitogen- And Stress-Activated P
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RPS6KA6 Protein, Human (Active, sf9, GST)
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Cat. No.: HY-P702651
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: RPS6KA6; RSK-4; Ribosomal Protein S6 Kinase A6; Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 6; RSK4; Ribosomal Protein S6 Kinase, 90kD, Polypeptide 6; 90 KDa Ribosomal Protein S6 Kinase 6; Non-Specific Serine/Threonine Protein Kinase; Ribosomal Protei
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RPS6KB2 Protein, Human (Inactive, sf9, His, GST)
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Cat. No.: HY-P703590
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: RPS6KB2; S6K-Beta; Ribosomal Protein S6 Kinase B2; P70 S6KB; STK14B; P70S6K2; P70-BETA; S6K2; P70S6Kb; SRK; S6Kbeta; Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 2; S6KB; Ribosomal Protein S6 Kinase, 70kD, Polypeptide 2; KLS; Serine/Threonine-Protein K
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S6K1/RPS6KB1 Protein, Human (T412E, sf9, His-GST)
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Cat. No.: HY-P705570
Synonyms: RPS6KB1; Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1; Prev. STK14A; 70 KDa Ribosomal Protein S6 Kinase 1; S6K1; Serine/Threonine Kinase 14 Alpha; P70(S6K)-Alpha; P70 Ribosomal S6 Kinase Alpha; PS6K; P70 S6 Kinase Alpha; S6K; RPS6KB1 Protein; Serine/Threonine-Protein Kinase 14A; P70 S6K-Alpha; Ribosomal Protein S6 Kinase Beta-1; P70-Alpha; Ribosomal Protein S6 Kinase I; P70-S6K 1; S6K-Beta-1; P70-S6K; P70 S6KA; P70S6K1; Ribosomal Protein S6 Kinase B1; Ribosomal Protein S6 Kinase, 70kD, Polypeptide 1
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RPS6KB2 Protein, Human (Active, sf9, GST)
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Cat. No.: HY-P706149
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: RPS6KB2; S6K-Beta; Ribosomal Protein S6 Kinase B2; P70 S6KB; STK14B; P70S6K2; P70-BETA; S6K2; P70S6Kb; SRK; S6Kbeta; Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 2; S6KB; Ribosomal Protein S6 Kinase, 70kD, Polypeptide 2; KLS; Serine/Threonine-Protein K
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RSK2 Protein, Human (sf9)
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Cat. No.: HY-P705881
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: RPS6KA3; Pp90RSK2; Prev. MRX19; RSK-2; Prev. CLS; Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3; RSK2; Ribosomal Protein S6 Kinase, 90kD, Polypeptide 3; Insulin-Stimulated Protein Kinase 1; Non-Specific Serine/Threonine Protein Kinase; HU-3; Epididymis Secretory Sperm Binding Protein; MAP Kinase-Activated Protein Kinase 1b; 90 KDa Ribosomal Protein S6 Kinase 3; Ribosomal Protein S6 Kinase Alpha-3; Ribosomal Protein S6 Kinase; MAPK-Activated Protein Kinase 1b; RPS6KA3 Protein; Ribosomal S6 Kinase 2; S6K-Alpha3; MAPKAP Kinase 1b; P90-RSK2; S6K-Alpha-3; P90RSK3; MAPKAPK-1b; XLID19; MAPKAPK1B; ISPK1; P90-RSK 3; RSK; Ribosomal Protein S6 Kinase A3; ISPK-1
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RSK1 Protein, Human (Active, sf9, His-GST)
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Cat. No.: HY-P706098
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: RPS6KA1; MAPKAPK1A; Ribosomal Protein S6 Kinase A1; P90-RSK 1; RSK1; P90RSK1; MAPKAPK1; P90S6K; P90Rsk; RSK-1; HU-1; DJ590P13.1 (Ribosomal Protein S6 Kinase, 90kD, Polypeptide 1); MAP Kinase-Activated Protein Kinase 1a; Ribosomal Protein S6 Kinase, 90kDa,
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RSK2 Protein, Human (Active, sf9, His-GST)
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Cat. No.: HY-P706099
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: RPS6KA3; Pp90RSK2; Prev. MRX19; RSK-2; Prev. CLS; Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3; RSK2; Ribosomal Protein S6 Kinase, 90kD, Polypeptide 3; Insulin-Stimulated Protein Kinase 1; Non-Specific Serine/Threonine Protein Kinase; HU-3; Epididymi
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
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Capetin (28-54), human
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- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
