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Cat. No.: HY-U00260

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CMI977

(Synonyms: LDP977)

CMI977 is a potent 5-Lipoxygenase (5-LO) inhibitor.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

CAS No.: 175212-04-1
Formule: C₁₆H₁₉FN₂O₄
Masse moléculaire:322.33

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (263 KB)

CMI977 Chemical Structure

CAS No.: 175212-04-1

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

CMI977 is a potent 5-Lipoxygenase (5-LO) inhibitor.

IC₅₀ & Target

5-LO

Voir tous les produits spécifiques à Isoform Lipoxygenase :

In Vitro

CMI977 is a potent 5-lipoxygenase (5-LO) inhibitor that intervenes in the production of leukotrienes and is presently being developed for the treatment of chronic asthma. It is a single enantiomer with an all-trans (2S,5S) configuration. Of the four isomers of CMI977, the S,S isomer is found to have the best biological activity and is selected for further development.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 175212-04-1
Masse moléculaire 322.33
Formule C₁₆H₁₉FN₂O₄
SMILES

O=C(N)N(CCC#C[C@H]1O[C@H](COC2=CC=C(F)C=C2)CC1)O
Synonyms

LDP977
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (263 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Xiong Cai, et al. Synthesis of CMI-977, a Potent 5-Lipoxygenase Inhibitor. Org. Proc. Res. Dev., 1999, 3 (1), pp 73-76.

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références

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CMI977

Voir tous les produits spécifiques à Isoform Lipoxygenase

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

CMI977 Related Classifications

HY-U00260 Related Classifications