A-1293102
A-1293102 is a potent and selective BCL-XL inhibitor that kills BCL-XL-dependent tumor cells.
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- CAS No.: 1565759-96-7
- Formule: C42H40F3N7O7S5
- Masse moléculaire:972.13
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| MOLT-4 | EC50 |
0.08 μM
Compound: 4; A-1293102
|
Cytotoxicity against human MOLT-4 cells assessed as reduction in cell viability measured after 48 hrs by celltiter-glo assay
Cytotoxicity against human MOLT-4 cells assessed as reduction in cell viability measured after 48 hrs by celltiter-glo assay
|
[PMID: 34141086] |
| RS4-11 | EC50 |
>5 μM
Compound: 4; A-1293102
|
Cytotoxicity against human RS4-11 cells assessed as reduction in cell viability measured after 48 hrs by celltiter-glo assay
Cytotoxicity against human RS4-11 cells assessed as reduction in cell viability measured after 48 hrs by celltiter-glo assay
|
[PMID: 34141086] |
Chemical Information
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CAS No. 1565759-96-7
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Masse moléculaire 972.13
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Formule C42H40F3N7O7S5
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SMILES
O=C(C1=C2C(CCN(C3=NC(C(NS(=O)(C4=CC(S(C(F)(F)F)(=O)=O)=C(C=C4)N[C@@H](CSC5=CC=CC=C5)CCN6CCOCC6)=O)=O)=CS3)C2)=CC=C1)NC7=NC8=CC=CC=C8S7
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Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)