ACT-373898
ACT-373898 is an inactive carboxylic acid metabolite of Macitentan. Macitentan is an orally active, non-peptide dual ETA and ETB (endothelin receptor) antagonist.
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- CAS No.: 1433875-14-9
- Formule: C15H17BrN4O5S
- Masse moléculaire:445.29
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
The elimination half-life (t1/2) is approximately 16 h for Macitentan, and ACT-373898 has a similar pharmacokinetic (PK) profile to Macitentan[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1433875-14-9
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Masse moléculaire 445.29
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Formule C15H17BrN4O5S
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SMILES
O=C(O)COC1=NC=NC(NS(=O)(NCCC)=O)=C1C2=CC=C(Br)C=C2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)