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Cat. No.: HY-146396

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Anticancer agent 51

Anticancer agent 51 (compound 3d) is a potent anticancer agent with an K_i of 731.62 nM. Anticancer agent 51 shows anticancer activity. Anticancer agent 51 has the potential for the research of prostate cancer.

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CAS No.: 2521777-38-6
Formule: C₂₂H₂₀F₃N₃O₂S
Masse moléculaire:447.47

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

Anticancer agent 51 Chemical Structure

CAS No.: 2521777-38-6

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

Voir tous les produits spécifiques à Isoform MetAP :

Cellular Effect

Cell Line	Type	Value	Description	References
DU-145	IC₅₀	62.2 μM Compound: 3d; SGK-606	Cytotoxicity against human DU-145 cells assessed as reduction in cell viability by MTT assay Cytotoxicity against human DU-145 cells assessed as reduction in cell viability by MTT assay	[PMID: 32998089]
LNCaP	IC₅₀	92.8 μM Compound: 3d; SGK-606	Cytotoxicity against human LNCaP cells assessed as reduction in cell viability by MTT assay Cytotoxicity against human LNCaP cells assessed as reduction in cell viability by MTT assay	[PMID: 32998089]
PC-3	IC₅₀	64.3 μM Compound: 3d; SGK-606	Cytotoxicity against human PC-3 cells assessed as reduction in cell viability by MTT assay Cytotoxicity against human PC-3 cells assessed as reduction in cell viability by MTT assay	[PMID: 32998089]

In Vitro

Anticancer agent 51 (compound 3d) shows anticancer activity with IC₅₀s of 64.3, 62.2, 92.8 μM for PC-3, DU-145, LNCaP cells, respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2521777-38-6
Masse moléculaire 447.47
Formule C₂₂H₂₀F₃N₃O₂S
SMILES

FC(F)(F)C(C=C1)=CC=C1NC(NNC([C@H](C2=CC3=C(C=C2)C=C(C=C3)OC)C)=O)=S
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Birgül K, et al. Synthesis, molecular modeling, in vivo study and anticancer activity against prostate cancer of (+) (S)-naproxen derivatives. Eur J Med Chem. 2020 Dec 15;208:112841. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Activité biologique
- Description
- In Vitro
Chemical Information
Pureté et documentation
Références

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Anticancer agent 51

Voir tous les produits spécifiques à Isoform MetAP

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Anticancer agent 51 Related Classifications

HY-146396 Related Classifications