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Bepranemab

(Synonyms: UCB 0107)
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Bepranemab is a humanized IgG4 monoclonal antibody that binds to the central region of tau protein. Bepranemab inhibits the seeding, aggregation of pathological tau protein and the spread of tau pathology to distal brain regions. Bepranemab is applicable to research related to Alzheimer's disease.

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  • Pureté: 99.90%
  • CAS No.: 2244960-75-4
  • Masse moléculaire:145.52 kDa
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Bepranemab
  • Experimental Validation Results for Bepranemab
  • Experimental Validation Results for Bepranemab
  • Bepranemab Chemical Structure
    Bepranemab Chemical Structure
CAS No.: 2244960-75-4
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Bepranemab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Trouvez votre distributeur local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG4 kappa

  • 1/16

    Immobilized Human Tau Protein (His Tag) can bind Bepranemab. The EC50 for this effect is 4.09 ng/mL.

  • 1/16

    Flow cytometric analysis of 1.5X106 SHSY5Y cells with Bepranemab (HY-P99471, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG4 kappa, Isotype Control (HY-P99003, blue) was used as the isotype control.

  • Bepranemab Chemical Structure
    1/16
  • Bepranemab
  • Immobilized Human Tau Protein (His Tag) can bind Bepranemab. The EC50 for this effect is 4.09 ng/mL.
  • Flow cytometric analysis of 1.5X106 SHSY5Y cells with Bepranemab (HY-P99471, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG4 kappa, Isotype Control (HY-P99003, blue) was used as the isotype control.