BGC4
BGC4 is a biphenyl-based gold(III) complex. BGC4 inhibits human recombinant thioredoxin reductase (TrxR) with an IC50 of 10.7 μM, exhibits cytotoxicity (IC50 for MDA-MB-231 is 5.4 μM), and induces apoptosis. BGC4 exhibits antitumor efficacy in mouse models.
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- Formule: C30H33AuClF3N3
- Masse moléculaire:725.02
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Chemical Information
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Masse moléculaire 725.02
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Formule C30H33AuClF3N3
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SMILES
CC(C)(C1=CC2=C(C=C1)C3=CC=C(C=C3[Au]2(C4N(C=CN4C5=NC=CC(C(F)(F)F)=C5)C)Cl)C(C)(C)C)C
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)