BIMAX2 acetate
Based on 1 Customer Validation
BIMAX2 acetate is a high affinity nuclear localization signal (NLS) peptide. BIMAX2 acetate can mimic the activity of the classical nuclear localization signal (cNLS) and competitively bind to importin α, thereby inhibiting the binding of cNLS-cargo proteins to importin α. BIMAX2 acetate can be used to study the role of RBBP4 in regulating nuclear import efficiency and cell senescence.
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- Pureté : 98.66%
- Formule: C146H254N64O41.xC2H4O2
- Masse moléculaire:3561.98 (free base)
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Stockage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Protocole
- Pureté et documentation
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Help & FAQs
Activité biologique
Description
Chemical Information
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Appearance Solid
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Masse moléculaire 3561.98 (free base)
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Formule C146H254N64O41.xC2H4O2
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Color White to off-white
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Sequence
Arg-Arg-Arg-Arg-Arg-Arg-Lys-Arg-Lys-Arg-Glu-Trp-Asp-Asp-Asp-Asp-Asp-Pro-Pro-Lys-Lys-Arg-Arg-Arg-Leu-Asp
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Sequence Shortening
RRRRRRKRKREWDDDDDPPKKRRRLD
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvant et solubilité
In Vitro:
H2O : ≥ 100 mg/mL
* "≥" means soluble, but saturation unknown.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
Pureté et documentation
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Fiche technique (252 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Hot Topics
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Topics
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Topics Cellular Senescence & Age-related Diseases
Cellular senescence is a stable state of cell-cycle arrest triggered by diverse forms of cellular stress, including telomere shortening, DNA damage, oncogene activation, mitochondrial dysfunction, oxidative stress, and chromatin perturbation.
2026-06-18
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Topics Senolytics and Senomorphic Strategies in Aging Research
Cellular senescence is a stable state of cell-cycle arrest triggered by DNA damage, telomere attrition, oncogenic signaling, and other forms of cellular stress.
2026-06-18
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Topics Molecular Spark of cGAS-STING-Mediated Cellular Senescence
Cellular senescence is a stress-response program characterized by irreversible cell-cycle arrest and the senescence-associated secretory phenotype (SASP), originally recognized as a tumor-suppressive mechanism and now considered a central process in aging biology, inflammation, and cancer research.
2026-06-18
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