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Cat. No.: HY-108909

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Chymopapain

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Chymopapain is a non-specific proteo-glycanase derived from the papaya plant. Chymopapain has neurotoxicity when injected into nerve bundles. Chymopapain directly into the intervertebral disc caused disc narrowing due to dissolution of the extruded material. Chymopapain has the potential for the research of herniated lumbar discs.

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CAS No.: 9001-09-6

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Chymopapain Chemical Structure

CAS No.: 9001-09-6

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Quantité

Sample (0.1mg)

In-stock

(In Japan)

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- In Vivo
- EC Number
- Enzyme Activity
- Unit Definition
Chemical Information
Solvant et solubilité
- In Vitro
Pureté et documentation
Références
Calculators
Help & FAQs
Bioz

Activité biologique

Description

Voir tous les produits spécifiques à Isoform Endogenous Metabolite :

In Vivo

Chymopapain (20-250 U, intraneural injection, single dose) causes dose-dependent nerve fiber damage in male Wistar rats^[2].
Chymopapain (100-10000 U, intraneural injection, single dose) causes nerve fiber damage at all doses in baboon^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

EC Number

3.4.4.11

Enzyme Activity

≥800 U/mg soild

Unit Definition

One unit is defined as the amount of enzyme that will hydrolyzes casein substrate to produce an amount of enzyme equivalent to 1µg of tyrosine in 1 min at 37°C and pH 7.0.

Chemical Information

CAS No. 9001-09-6
Appearance Solid
Color White to off-white
SMILES

[Chymopapain]
Structure Classification
- Others
Initial Source
- Endogenous metabolite
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvant et solubilité

In Vitro:

H₂O : ≥ 100 mg/mL

* "≥" means soluble, but saturation unknown.

View the Complete Stock Solution Preparation Table

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (266 KB)
SDS (557 KB)
- English - EN (557 KB)
- Français - FR (557 KB)
- Deutsch - DE (557 KB)
- Norwegian - NO (557 KB)
- Español - ES (557 KB)
- Swedish - SV (557 KB)
- Italian - IT (557 KB)
- Portuguese - PT (557 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Knezevic NN, et al. Treatment of chronic low back pain - new approaches on the horizon. J Pain Res. 2017 May 10;10:1111-1123. [Content Brief]

[2]. Mackinnon SE, et al. Peripheral nerve injury by chymopapain injection. J Neurosurg. 1984 Jul;61(1):1-8. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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