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Cat. No.: HY-161889

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DCSM06-05

DCSM06-05 is a potent SMARCA2-BRD inhibitor with an IC₅₀ value of 9 µM, a K_d value of 22.4 µM.

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CAS No.: 880811-10-9
Formule: C₂₁H₂₁FN₂O₂
Masse moléculaire:352.40

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

DCSM06-05 Chemical Structure

CAS No.: 880811-10-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

DCSM06-05 is a potent SMARCA2-BRD inhibitor with an IC₅₀ value of 9 µM, a K_d value of 22.4 µM^[1].

IC₅₀ & Target^[1]

Brd

9 μM (IC₅₀)

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Chemical Information

CAS No. 880811-10-9
Masse moléculaire 352.40
Formule C₂₁H₂₁FN₂O₂
SMILES

COC1=CC(CNCC2=CC=CC=N2)=CC=C1OCC3=C(F)C=CC=C3
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Lu T, et al. Identification of small molecule inhibitors targeting the SMARCA2 bromodomain from a high-throughput screening assay. Acta Pharmacol Sin. 2018 Sep;39(9):1544-1552. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références

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DCSM06-05

Voir tous les produits spécifiques à Isoform SWI/SNF Complex

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

DCSM06-05 Related Classifications

HY-161889 Related Classifications