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Eptinezumab

(Synonyms: ALD-403)
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Eptinezumab (ALD-403) is a human monoclonal antibody targeting the α and β subtypes of human calcitonin gene-related peptide (CGRP). Eptinezumab binds to the CGRP ligand and blocks its binding to endogenous CGRP receptors, thereby inhibiting receptor activation. Eptinezumab can be used in research related to migraine.

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  • Pureté: 99.90%
  • CAS No.: 1644539-04-7
  • Masse moléculaire:143.36 kDa
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Eptinezumab
  • Experimental Validation Results for Eptinezumab
  • Experimental Validation Results for Eptinezumab
  • Eptinezumab Chemical Structure
    Eptinezumab Chemical Structure
CAS No.: 1644539-04-7
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Eptinezumab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Trouvez votre distributeur local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Flow cytometric analysis of 1X106 A549 cells with Eptinezumab (HY-P99017, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • 1/16

    Immobilized Human-α-CGRP can bind Eptinezumab. The EC50 for this effect is 55.91 ng/mL.

  • Eptinezumab Chemical Structure
    1/16
  • Eptinezumab
  • Flow cytometric analysis of 1X106 A549 cells with Eptinezumab (HY-P99017, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • Immobilized Human-α-CGRP can bind Eptinezumab. The EC50 for this effect is 55.91 ng/mL.