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Cat. No.: HY-100410R

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FCCP (Standard)

(Synonyms: Carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone (Standard))

1 Cited Publications

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Based on 1 publication(s) in Google Scholar

FCCP (Standard) is the analytical standard of FCCP. This product is intended for research and analytical applications. FCCP is an uncoupler of oxidative phosphorylation (OXPHOS) in mitochondria. FCCP induces activation of PINK1 leading to Parkin Ser65 phosphorylation.

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Pureté: 99.21%
CAS No.: 370-86-5
Formule: C₁₀H₅F₃N₄O
Masse moléculaire:254.17

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Please store the product under the recommended conditions in the Certificate of Analysis.

FCCP (Standard) Chemical Structure

CAS No.: 370-86-5

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Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 370-86-5
Appearance Solid
Masse moléculaire 254.17
Formule C₁₀H₅F₃N₄O
Color Light yellow to yellow
SMILES

N#C/C(C#N)=N/NC1=CC=C(OC(F)(F)F)C=C1
Synonyms

Carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone (Standard)
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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J Virol

Coronavirus infectious bronchitis virus spike protein inhibits FUNDC1-mediated mitophagy to prevent nucleocapsid protein degradation. [Abstract]

2026 May 19;100(5):e0180025. PMID: 42007729

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

SDS (420 KB)
- English - EN (420 KB)
- Français - FR (420 KB)
- Deutsch - DE (420 KB)
- Norwegian - NO (420 KB)
- Español - ES (420 KB)
- Swedish - SV (420 KB)
- Italian - IT (420 KB)
- Korean - KR (420 KB)
- Portuguese - PT (420 KB)
COA (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Connop BP et al.Novel effects of FCCP [carbonyl cyanide p-(trifluoromethoxy)phenylhydrazone] on amyloid precursor protein processing. J Neurochem. 1999 Apr;72(4):1457-65. [Content Brief]

[2]. Tanpradit N, et al. Carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone (FCCP) pre-exposure ensures follicle integrity during in vitro culture of ovarian tissue but not during cryopreservation in the domestic cat model. J Assist Reprod Genet. 2016 Dec;33(12):1621-1631. Epub 2016 Sep 17. [Content Brief]

[3]. Kondapalli C, et al. PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65. Open Biol. 2012 May;2(5):120080. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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FCCP (Standard)

1 Cited Publications

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FCCP (Standard)

Publications Citing Use of MedChemExpress (MCE) FCCP (Standard)

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Publications (1)

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FCCP (Standard) Related Classifications

HY-100410R Related Classifications