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Firastotug

(Synonyms: ADG116)
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Firastotug (ADG116) is an anti-CTLA‑4 IgG1 antibody that exerts antitumor effects through partial blockade of CD80/86 and enhancement of ADCC-mediated intratumoral Treg depletion. Firastotug can be used in research related to advanced/metastatic solid tumors.

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  • Pureté : 98.62%
  • CAS No.: 2750031-14-0
  • Masse moléculaire:145.05 kDa
  • Stockage:
    Shipping with dry ice

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Firastotug
  • Experimental Validation Results for Firastotug
  • Experimental Validation Results for Firastotug
  • Firastotug Chemical Structure
    Firastotug Chemical Structure
CAS No.: 2750031-14-0
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Firastotug Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Trouvez votre distributeur local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Immobilized CTLA-4 Protein, Human (HEK293, HY-P72959) can bind Firastotug. The EC50 for this effect is 2.057 ng/mL.

  • 1/16

    Flow Cytometry analysis of Raji cells labelling CTLA4 (red) with Firastotug (anti-CTLA4) (HY-P990041). Cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Firastotug Chemical Structure
    1/16
  • Firastotug
  • Immobilized CTLA-4 Protein, Human (HEK293, HY-P72959) can bind Firastotug. The EC50 for this effect is 2.057 ng/mL.
  • Flow Cytometry analysis of Raji cells labelling CTLA4 (red) with Firastotug (anti-CTLA4) (HY-P990041). Cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).