Fluoroestradiol
Fluoroestradiol is an Estrogen receptor PET imaging tracer precursor. Fluoroestradiol, when radiolabeled with 18F, can be used as an Estrogen receptor PET imaging tracer. 18F-Fluoroestradiol exhibits the highest uptake selectivity and target-to-background ratio among
several 18F-labeled estrogens. 18F-Fluoroestradiol has demonstrated Estrogen receptor expression in normal brain tissues and in meningiomas. 18F-Fluoroestradiol can quantify regional Estrogen receptor expression in breast cancer. 18F-Fluoroestradiol has potential applications in assessing and monitoring heterogeneity in ovarian cancer.
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- CAS No.: 84693-92-5
- Formule: C18H23FO2
- Masse moléculaire:290.38
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
Description
several 18F-labeled estrogens. 18F-Fluoroestradiol has demonstrated Estrogen receptor expression in normal brain tissues and in meningiomas. 18F-Fluoroestradiol can quantify regional Estrogen receptor expression in breast cancer. 18F-Fluoroestradiol has potential applications in assessing and monitoring heterogeneity in ovarian cancer[1].
Chemical Information
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CAS No. 84693-92-5
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Masse moléculaire 290.38
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Formule C18H23FO2
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SMILES
C[C@@]12[C@]([C@]3([C@@](C=4C(CC3)=CC(O)=CC4)(CC1)[H])[H])(C[C@H](F)[C@@H]2O)[H]
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Keywords
- Fluoroestradiol
- 84693-92-5
- Estrogen Receptor/ERR
- Radionuclide-Drug Conjugates (RDCs)
- blood-brain barrier
- immunohistochemical methods
- ER-expressing tissues
- ovarian epithelial origin tumors
- murine breast cancer xenografts
- hormone therapy
- estrogen receptor
- immature rats
- uterine
- breast cancer
- ER
- Inhibitor
- inhibitor
- inhibit