Human UGT1A7
Human UGT1A7 is a UDP-glucuronosyltransferase. UGT1A7 catalyzes the glucuronidation of hydrophobic substrates, polycyclic aromatic hydrocarbons, dietary heterocyclic amines, and 1-Hydroxypyrene (HY-W014075). Human UGT1A7 is applicable to research related to sporadic colorectal cancer.
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Chemical Information
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Activité biologique
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UGT1A7 |
Human UGT1A7 catalyzes the glucuronidation of 1-Hydroxypyrene (HY-W014075), and its apparent Km value is determined to be 12 μM via sensitive fluorescence HPLC analysis[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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SMILES
[Human UGT1A7]
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Strassburg CP, et al. Polymorphisms of the human UDP-glucuronosyltransferase (UGT) 1A7 gene in colorectal cancer. Gut. 2002 Jun;50(6):851-6. [Content Brief]
[2]. Luukkanen L, et al. Glucuronidation of 1-hydroxypyrene by human liver microsomes and human UDP-glucuronosyltransferases UGT1A6, UGT1A7, and UGT1A9: development of a high-sensitivity glucuronidation assay for human tissue. Drug metabolism and disposition: the biological fate of chemicals. 2001 Aug;29(8):1096-101. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Human UGT1A7 Related Classifications
HY-E72109 Related Classifications
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