2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. 1-Hydroxypyrene

1-Hydroxypyrene 

Cat. No.: HY-W014075 Purity: 99.84%
COA Handling Instructions

1-Hydroxypyrene, a biomarker of exposure to polycyclic aromatic hydrocarbons (PAHs), is analyzed in urine samples. 1-Hydroxypyrene is the major biomarker of exposure to pyrenes.

For research use only. We do not sell to patients.

1-Hydroxypyrene Chemical Structure

1-Hydroxypyrene Chemical Structure

CAS No. : 5315-79-7

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500 mg USD 50 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

1-Hydroxypyrene, a biomarker of exposure to polycyclic aromatic hydrocarbons (PAHs), is analyzed in urine samples. 1-Hydroxypyrene is the major biomarker of exposure to pyrenes[1].

IC50 & Target

Human Endogenous Metabolite

 

Molecular Weight

218.26

Appearance

Solid

Formula

C16H10O
CAS No.
SMILES

OC1=C(C2=C34)C=CC4=CC=CC3=CC=C2C=C1
Structure Classification
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (229.08 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.5817 mL 22.9085 mL 45.8169 mL
5 mM 0.9163 mL 4.5817 mL 9.1634 mL
10 mM 0.4582 mL 2.2908 mL 4.5817 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (11.45 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (11.45 mM); Clear solution

*All of the co-solvents are available by MCE.
Purity & Documentation

Purity: 99.84%

COA (256 KB) HNMR (117 KB) RP-HPLC (189 KB)

Handling Instructions (2659 KB)
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

1-Hydroxypyrene5315-79-7Endogenous MetabolitepolycyclicaromatichydrocarbonsPAHsbiomarkerpyrenesInhibitorinhibitorinhibit

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