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Cat. No.: HY-N12693

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Isobiflorin

Isobiflorin is an anti-inflammatory agent and can be isolated from Syzygium aromaticum. Isobiflorin inhibits LPS-induced PGE2 production with an IC₅₀ value of 46.0 μM.

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CAS No.: 152041-16-2
Formule: C₁₆H₁₈O₉
Masse moléculaire:354.31

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

Isobiflorin Chemical Structure

CAS No.: 152041-16-2

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Activité biologique
- Description
- Cellular Effect
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

Isobiflorin is an anti-inflammatory agent and can be isolated from Syzygium aromaticum. Isobiflorin inhibits LPS-induced PGE2 production with an IC₅₀ value of 46.0 μM^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
RAW264.7	IC₅₀	>60 μM Compound: 2	Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production preincubated for 1 hr followed by LPS challenge for 24 hrs by Griess assay Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production preincubated for 1 hr followed by LPS challenge for 24 hrs by Griess assay	[PMID: 26977531]
RAW264.7	IC₅₀	46 μM Compound: 2	Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced PGE2 production preincubated for 1 hr followed by LPS challenge for 24 hrs by ELISA method Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced PGE2 production preincubated for 1 hr followed by LPS challenge for 24 hrs by ELISA method	[PMID: 26977531]

Chemical Information

CAS No. 152041-16-2
Masse moléculaire 354.31
Formule C₁₆H₁₈O₉
SMILES

OC1=CC(O)=C(C(C=C(O2)C)=O)C2=C1[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)CO
Structure Classification
- Saccharides
- Monosaccharides
Initial Source
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Lee HH, et al. Biflorin, Isolated from the Flower Buds of Syzygium aromaticum L., Suppresses LPS-Induced Inflammatory Mediators via STAT1 Inactivation in Macrophages and Protects Mice from Endotoxin Shock. J Nat Prod. 2016 Apr 22;79(4):711-20. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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