ME3221
ME3221 is an angiotensin AT1 receptor antagonist that effectively antagonizes the pressor response to angiotensin II in rats and marmosets without affecting the hypotensive response to bradykinin. It demonstrates potent antihypertensive effects in renal hypertensive rats and spontaneously hypertensive rats (SHR). ME3221's repeated administration in SHR results in sustained and stable hypotensive effects without affecting heart rate, indicating its potential for studying both renal and essential hypertension.
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- CAS No.: 139958-16-0
- Formule: C22H21N5O2
- Masse moléculaire:387.43
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
Chemical Information
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CAS No. 139958-16-0
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Masse moléculaire 387.43
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Formule C22H21N5O2
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SMILES
COC1=C(C=C(C)N=C1C)OCC2=CC=C(C=C2)C3=C(C=CC=C3)C4=NN=NN4
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ME3221 Related Classifications
HY-121550 Related Classifications
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