Murrayanine
Murrayanine is a dimeric pyranoquinoline alkaloid, a mixture of two enantiomers with a predominant configuration on the chiral axis.
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- CAS No.: 723-97-7
- Formule: C14H11NO2
- Masse moléculaire:225.24
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| KB | IC50 |
72.23 μM
Compound: 15
|
Cytotoxicity against human KB cells by resazurin microplate assay
Cytotoxicity against human KB cells by resazurin microplate assay
|
[PMID: 21302964] |
| NCI-H187 | IC50 |
11.45 μM
Compound: 15
|
Cytotoxicity against human NCI-H187 by resazurin microplate assay
Cytotoxicity against human NCI-H187 by resazurin microplate assay
|
[PMID: 21302964] |
| Neutrophil | IC50 |
3.5 μM
Compound: 21
|
Antiinflammatory activity in human neutrophil assessed as inhibition of FMLP/CB-induced superoxide anion generation pretreated for 5 mins by spectrophotometry
Antiinflammatory activity in human neutrophil assessed as inhibition of FMLP/CB-induced superoxide anion generation pretreated for 5 mins by spectrophotometry
|
[PMID: 24798144] |
| Neutrophil | IC50 |
3.9 μM
Compound: 21
|
Antiinflammatory activity in human neutrophil assessed as inhibition of FMLP/CB-induced elastase release for 5 mins
Antiinflammatory activity in human neutrophil assessed as inhibition of FMLP/CB-induced elastase release for 5 mins
|
[PMID: 24798144] |
| Vero | IC50 |
>200 μM
Compound: 15
|
Cytotoxicity against african green monkey Vero cells by green fluorescent protein microplate assay
Cytotoxicity against african green monkey Vero cells by green fluorescent protein microplate assay
|
[PMID: 21302964] |
Chemical Information
-
CAS No. 723-97-7
-
Masse moléculaire 225.24
-
Formule C14H11NO2
-
SMILES
O=CC1=CC2=C(NC3=C2C=CC=C3)C(OC)=C1
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Structure Classification
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Initial Source
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Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)