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Cat. No.: HY-110014

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Noladin ether

Name: Noladin ether
Brand: MedChemExpress
SKU: HY-110014
Price: 250.00 USD
Availability: InStock
Rating: 5 (1 reviews)

1 Cited Publications

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Noladin ether is a potent and selective agonist of cannabinoid CB₁ receptor, with a K_i of 21.2 nM. Noladin ether can cause hypothermia, intestinal immobility, and mild antinociception.
The product specifications provided below refer solely to the active content of Noladin ether.

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Pureté : 98.00%
CAS No.: 222723-55-9
Formule: C₂₃H₄₀O₃
Masse moléculaire:364.56

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Shipping with dry ice

Solution, -20°C, 1 year

Noladin ether Chemical Structure

CAS No.: 222723-55-9

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Publications (1)
Pureté et documentation
Références
Calculators
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Activité biologique

Description

Noladin ether is a potent and selective agonist of cannabinoid CB₁ receptor, with a K_i of 21.2 nM. Noladin ether can cause hypothermia, intestinal immobility, and mild antinociception^[1].
The product specifications provided below refer solely to the active content of Noladin ether.

IC₅₀ & Target

^[1]

CB1

21.2 nM (Ki)

CB2

>3 mM (Ki)

Voir tous les produits spécifiques à Isoform Cannabinoid Receptor :

Chemical Information

CAS No. 222723-55-9
Appearance Liquid
Masse moléculaire 364.56
Formule C₂₃H₄₀O₃
Color Colorless to light yellow
SMILES

CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCCOC(CO)CO
Livraison

Shipping with dry ice.
Stockage

Solution, -20°C, 1 year

Publications (1)

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J Headache Pain

Activation of CB1R alleviates central sensitization by regulating HCN2-pNR2B signaling in a chronic migraine rat model. [Abstract]

2023 Apr 21;24(1):44. PMID: 37085778

Noladin ether purchased from MedChemExpress. Usage Cited in: J Headache Pain. 2023 Apr 21;24(1):44. [Abstract]

ZD 7288 (5 μg; i.c.) robustly reduced the number of c-Fos-positive cells and the average fluorescence intensity of CGRP and SP in CM mice.

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (265 KB)
SDS (419 KB)
- English - EN (419 KB)
- Français - FR (419 KB)
- Deutsch - DE (419 KB)
- Norwegian - NO (419 KB)
- Español - ES (419 KB)
- Swedish - SV (419 KB)
- Italian - IT (419 KB)
- Korean - KR (419 KB)
- Portuguese - PT (419 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Hanus L, et, al. 2-arachidonyl glyceryl ether, an endogenous agonist of the cannabinoid CB1 receptor. Proc Natl Acad Sci U S A. 2001 Mar 27;98(7):3662-5. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Keywords

Noladin ether

1 Cited Publications

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Activité biologique
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Chemical Information
Publications (1)
Pureté et documentation
Références

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Noladin ether purchased from MedChemExpress. Usage Cited in: J Headache Pain. 2023 Apr 21;24(1):44. [Abstract]

Customer Validation
ZD 7288 (5 μg; i.c.) robustly reduced the number of c-Fos-positive cells and the average fluorescence intensity of CGRP and SP in CM mice.

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Noladin ether

Publications Citing Use of MedChemExpress (MCE) Noladin ether

Voir tous les produits spécifiques à Isoform Cannabinoid Receptor