Factor D
Factor D is a small serine protease that acts as the rate-limiting enzyme of the alternative complement pathway. Unusually, it circulates in an already active form and displays high specificity for a single physiological substrate: factor B, which it cleaves only when B is bound to C3b, generating the C3bBb convertase. The mature enzyme is released mainly by adipocytes, linking complement to metabolism. Because factor D controls the amplification loop, it is a prime drug target, and small-molecule inhibitors such as danicopan are used clinically to curb complement-driven hemolysis. Recombinant factor D supports convertase reconstitution and inhibitor screening.
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Factor D Protéines Recombinantes (8)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formule: Human
- Masse moléculaire: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
