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Cat. No.: HY-N1251

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Scholaricine

Scholaricine (compound 13 ) is an alkaloid isolated from the leaf and stem-bark extracts of Alstonia spatulata. Scholaricine reverse multidrug resistance in vincristine-resistant KB cells with an IC₅₀ value of 13.35 μM.

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CAS No.: 99694-90-3
Formule: C₂₀H₂₄N₂O₄
Masse moléculaire:356.42

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (276 KB)

Scholaricine Chemical Structure

CAS No.: 99694-90-3

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
Chemical Information
Protocole (1)
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

Cellular Effect

Cell Line	Type	Value	Description	References
KB/VJ300	IC₅₀	1.15 μg/mL Compound: 13	Cytotoxicity against human vincristine-resistant KB/VJ300 cells in presence of vincristine Cytotoxicity against human vincristine-resistant KB/VJ300 cells in presence of vincristine	[PMID: 21043460]
KB/VJ300	IC₅₀	13.35 μg/mL Compound: 13	Cytotoxicity against human vincristine-resistant KB/VJ300 cells Cytotoxicity against human vincristine-resistant KB/VJ300 cells	[PMID: 21043460]

Chemical Information

CAS No. 99694-90-3
Masse moléculaire 356.42
Formule C₂₀H₂₄N₂O₄
SMILES

COC(C1=C2[C@]3(C4=CC=CC(O)=C4N2)[C@@]5([H])N(C[C@]([C@]1([H])C5)([H])[C@@H](O)C)CC3)=O
Structure Classification
- Alkaloids
- Other Alkaloids
Initial Source
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocole

All Cell Biology

Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (276 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Shin-Jowl Tan , et al. Strychnan and secoangustilobine A type alkaloids from Alstonia spatulata. Revision of the C-20 configuration of scholaricine. J Nat Prod. 2010, 73, 11. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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