SF 11
Based on 1 Customer Validation
SF 11 is a potent and brain penetrant neuropeptide Y Y2 receptor antagonist (IC50=199 nM). Antidepressant-like activity.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté: 98.76%
- CAS No.: 443292-81-7
- Formule: C27H30N2O2S
- Masse moléculaire:446.60
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Stockage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
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Voir tous les produits spécifiques à Isoform Neuropeptide Y Receptor
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Activité biologique
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NPY Y2 receptor 199 nM (IC50) |
Chemical Information
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CAS No. 443292-81-7
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Appearance Solid
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Masse moléculaire 446.60
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Formule C27H30N2O2S
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Color White to off-white
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SMILES
OC(C1=CC=CC=C1)(C2=CC=CC=C2)C3CCN(C(NC4=CC=C(OCC)C=C4)=S)CC3
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvant et solubilité
DMSO : 250 mg/mL (559.79 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (271 KB)
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SDS (392 KB)
- English - EN (392 KB)
- Français - FR (392 KB)
- Deutsch - DE (392 KB)
- Norwegian - NO (392 KB)
- Español - ES (392 KB)
- Swedish - SV (392 KB)
- Italian - IT (392 KB)
- Korean - KR (392 KB)
- Portuguese - PT (392 KB)
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Instruction de manipulation (2659 KB)
Références
[1]. Domin H, et al. Characterization of the Brain Penetrant Neuropeptide Y Y2 Receptor Antagonist SF-11. ACS Chem Neurosci. 2019;10(8):3454-3463. [Content Brief]
[2]. Brothers SP, et al. Selective and brain penetrant neuropeptide y y2 receptor antagonists discovered by whole-cell high-throughput screening. Mol Pharmacol. 2010;77(1):46-57. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.2391 mL | 11.1957 mL | 22.3914 mL | 55.9785 mL |
| 5 mM | 0.4478 mL | 2.2391 mL | 4.4783 mL | 11.1957 mL | |
| 10 mM | 0.2239 mL | 1.1196 mL | 2.2391 mL | 5.5979 mL | |
| 15 mM | 0.1493 mL | 0.7464 mL | 1.4928 mL | 3.7319 mL | |
| 20 mM | 0.1120 mL | 0.5598 mL | 1.1196 mL | 2.7989 mL | |
| 25 mM | 0.0896 mL | 0.4478 mL | 0.8957 mL | 2.2391 mL | |
| 30 mM | 0.0746 mL | 0.3732 mL | 0.7464 mL | 1.8660 mL | |
| 40 mM | 0.0560 mL | 0.2799 mL | 0.5598 mL | 1.3995 mL | |
| 50 mM | 0.0448 mL | 0.2239 mL | 0.4478 mL | 1.1196 mL | |
| 60 mM | 0.0373 mL | 0.1866 mL | 0.3732 mL | 0.9330 mL | |
| 80 mM | 0.0280 mL | 0.1399 mL | 0.2799 mL | 0.6997 mL | |
| 100 mM | 0.0224 mL | 0.1120 mL | 0.2239 mL | 0.5598 mL |
SF 11 Related Classifications
HY-107731 Related Classifications
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