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Solbinsiran

(Synonyms: LY3561774)

Solbinsiran is a siRNA targeted to hepatic ANGPTL3.

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  • CAS No.: 2718150-11-7
  • Formule: C653H859O412N229F11P57S6
  • Masse moléculaire:20674.90
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    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Solbinsiran Chemical Structure
    Solbinsiran Chemical Structure
CAS No.: 2718150-11-7
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  • Solbinsiran Chemical Structure
    Solbinsiran Chemical Structure RNA, ([4'-de(hydroxymethyl)-4'-[(hydroxymethoxyphosphinyl)methoxy]]Um-sp-(2'-deoxy-2'-fluoro)G-sp-(2'-deoxy-2'-fluoro)U-sp-(2'-deoxy-2'-fluoro)A-(2'-deoxy-2'-fluoro)U-Am-(2'-deoxy-2'-fluoro)A-Cm-Cm-(2'-deoxy-2'-fluoro)U-Um-Cm-Cm-(2'-deoxy-2'-fluoro)A-Um-Um-Um-Um-Gm-Am-sp-Gm-sp-Gm), complex with RNA (Um-sp-Cm-Am-Am-Am-Am-Um-(2'-deoxy-2'-fluoro)G-(2'-deoxy-2'-fluoro)G-(2'-deoxy-2'-fluoro)A-(2'-deoxy-2'-fluoro)A-Gm-Gm-Um-Um-Am-Um-Am-Cm-Am-Gm-Cm-Am-Gm-Cm-Cm-Gm-[2'-O-[[2-[2-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]ethoxy]ethoxy]methyl]]A-[2'-O-[[2-[2-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]ethoxy]ethoxy]methyl]]A-[2'-O-[[2-[2-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]ethoxy]ethoxy]methyl]]A-Gm-Gm-Cm-Um-Gm-Cm) (1:1)
    1/16
  • RNA, ([4'-de(hydroxymethyl)-4'-[(hydroxymethoxyphosphinyl)methoxy]]Um-sp-(2'-deoxy-2'-fluoro)G-sp-(2'-deoxy-2'-fluoro)U-sp-(2'-deoxy-2'-fluoro)A-(2'-deoxy-2'-fluoro)U-Am-(2'-deoxy-2'-fluoro)A-Cm-Cm-(2'-deoxy-2'-fluoro)U-Um-Cm-Cm-(2'-deoxy-2'-fluoro)A-Um-Um-Um-Um-Gm-Am-sp-Gm-sp-Gm), complex with RNA (Um-sp-Cm-Am-Am-Am-Am-Um-(2'-deoxy-2'-fluoro)G-(2'-deoxy-2'-fluoro)G-(2'-deoxy-2'-fluoro)A-(2'-deoxy-2'-fluoro)A-Gm-Gm-Um-Um-Am-Um-Am-Cm-Am-Gm-Cm-Am-Gm-Cm-Cm-Gm-[2'-O-[[2-[2-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]ethoxy]ethoxy]methyl]]A-[2'-O-[[2-[2-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]ethoxy]ethoxy]methyl]]A-[2'-O-[[2-[2-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]ethoxy]ethoxy]methyl]]A-Gm-Gm-Cm-Um-Gm-Cm) (1:1)