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Cat. No.: HY-134192

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TH301

TH301 is a Phenylpyrazole derivative. TH301 selectively stabilize CRY2. TH301 dose-dependently prolongs circadian period.

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CAS No.: 450338-32-6
Formule: C₂₄H₂₄ClN₃O₄S
Masse moléculaire:485.98

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

TH301 Chemical Structure

CAS No.: 450338-32-6

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
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Calculators
Help & FAQs
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Bioz

Activité biologique

Description

TH301 is a Phenylpyrazole derivative. TH301 selectively stabilize CRY2. TH301 dose-dependently prolongs circadian period^[1].

IC₅₀ & Target^[1]

CRY2

Voir tous les produits spécifiques à Isoform Cryptochrome :

CRY1
CRY2

Chemical Information

CAS No. 450338-32-6
Masse moléculaire 485.98
Formule C₂₄H₂₄ClN₃O₄S
SMILES

O=C(C1(C2=CC=C(Cl)C=C2)CCCC1)NC3=C4C(CS(C4)(=O)=O)=NN3C5=CC=C(OC)C=C5
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Miller S, et al. Isoform-selective regulation of mammalian cryptochromes. Nat Chem Biol. 2020 Jun;16(6):676-685. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Chemical Information
Pureté et documentation
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TH301

Voir tous les produits spécifiques à Isoform Cryptochrome

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

TH301 Related Classifications

HY-134192 Related Classifications