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Cat. No.: HY-182756

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TREM2 modulator-1

TREM2 modulator-1 is a TREM2 modulator with an EC₅₀ categorized as A and Emax of ++, and can be found in relevant research contexts. TREM2 modulator-1 modulates Triggering Receptor Expressed on Myeloid Cells 2. TREM2 modulator-1 can be used for the research of neurodegenerative diseases.

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CAS No.: 3070235-71-8
Formule: C₂₅H₂₂Cl₂FN₅O₂
Masse moléculaire:514.38

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Please store the product under the recommended conditions in the Certificate of Analysis.

TREM2 modulator-1 Chemical Structure

CAS No.: 3070235-71-8

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références
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Activité biologique

Description

IC₅₀ & Target^[1]

TREM-2

Voir tous les produits spécifiques à Isoform TREM receptor :

In Vitro

TREM2 modulator-1 (Example 18B) modulates TREM2 in HEK293/DAP12⁺TREM2 cells and activates phosphorylated Syk AlphaScreen signals, with an EC₅₀ of <10 nM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 3070235-71-8
Masse moléculaire 514.38
Formule C₂₅H₂₂Cl₂FN₅O₂
SMILES

FC1=C(C=CC(Cl)=C1)C2=NC([C@H]3C[C@@H](C4=CN(C5CC5)N=C4)OCC3)=CN6C2=NC(C)=C(Cl)C6=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Jakob Busch-Petersen, et al. Trem2 modulators. WO2025017059A1. WIPO (PCT). 2024-07-17.

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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- IC₅₀ & Target
- In Vitro
Chemical Information
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TREM2 modulator-1

Voir tous les produits spécifiques à Isoform TREM receptor

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

TREM2 modulator-1 Related Classifications

HY-182756 Related Classifications