(+)-Yahazunone
(+)-Yahazunone is a bioactive marine pimarane-type meroterpenoid antifungal agent, with an EC50 value of 28.7 μM against Sclerotinia sclerotiorum. (+)-Yahazunone is applicable to studies related to Sclerotinia sclerotiorum infection.
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- CAS No.: 1376654-34-0
- Formule: C21H30O3
- Masse moléculaire:330.46
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
In Vitro
(+)-Yahazunone potently inhibits mycelium growth of Sclerotinia sclerotiorum with an EC50 of 28.7 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 1376654-34-0
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Masse moléculaire 330.46
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Formule C21H30O3
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SMILES
C[C@@]12[C@H]([C@](O)(CC[C@@]1([H])C(C)(CCC2)C)C)CC(C(C=C3)=O)=CC3=O
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Structure Classification
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Initial Source
Dictyopteris undulata Okamura
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocole
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)