Chktide acetate
Based on 1 Customer Validation
Chktide acetate is a synthetic peptide substrate applicable for activity assays of Chk1 kinase and cyk/CaMKII. Chktide acetate contains the Ser53 phosphorylation site of Xenopus cyclin B2.
For research use only. We do not sell to patients.
- Purity: 99.46%
- Formula: C115H198N40O33S·xC2H4O2
- Molecular Weight:2701.12 (free base)
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Chk1 |
CaMK II |
Chktide acetate serves as a standard synthetic substrate for Chk1 serine protein kinase assays and can be used for the quantitative detection of Chk1 catalytic activity[1].
Chktide acetate contains the Ser53 phosphorylation site of Xenopus cyclin B2, and upon phosphorylation, it induces a prophase-like premature phenotype in fibroblasts[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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Molecular Weight 2701.12 (free base)
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Formula C115H198N40O33S·xC2H4O2
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Color White to off-white
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Sequence
Lys-Lys-Lys-Val-Ser-Arg-Ser-Gly-Leu-Tyr-Arg-Ser-Pro-Ser-Met-Pro-Glu-Asn-Leu-Asn-Arg-Pro-Arg
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Sequence Shortening
KKKVSRSGLYRSPSMPENLNRPR
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H2O : 50 mg/mL (Need ultrasonic)
Purity & Documentation
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Data Sheet (278 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1].
Walker M, et al. Chk1 C-terminal regulatory phosphorylation mediates checkpoint activation by de-repression of Chk1 catalytic activity. Oncogene. 2009 Jun 18;28(24):2314-23.
[Content Brief]
[2]. Stevens I, et al. Identification of cyk, a cyclin B2 kinase, as a novel calcium/calmodulin-dependent protein kinase II and its role during Xenopus laevis oocyte maturation. Experimental cell research. 1999 Nov 01;252(2):303-18. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Chktide acetate Related Classifications
HY-P5961A Related Classifications
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