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Cat. No.: HY-187235

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ClpP1P2-IN-1

ClpP1P2-IN-1 is a protease inhibitor targeting ClpP1P2 of Mycobacterium tuberculosis, with a K_i value of 0.04 μM. ClpP1P2-IN-1 inhibits the growth of Mycobacterium tuberculosis and shows low cytotoxicity against mammalian kidney cells. ClpP1P2-IN-1 can be used in the research of tuberculosis.

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CAS No.: 3069900-75-7
화학식: C₂₆H₂₇F₅N₄O₄S₂
분자량:618.64

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

ClpP1P2-IN-1 Chemical Structure

CAS No.: 3069900-75-7

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

In Vitro

ClpP1P2-IN-1 (ClpP-1697) inhibits growth of Mycobacterium tuberculosis strain H37Rv with an average MIC of 0.11 μg/mL in Middlebrook 7H12 medium without catalase^[1].
ClpP1P2-IN-1 has no significant cytotoxicity against Vero green monkey kidney cells, with an IC₅₀ >20 μg/mL^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 3069900-75-7
분자량 618.64
화학식 C₂₆H₂₇F₅N₄O₄S₂
SMILES

FCC1=C(C2=NC=C(C(N[C@@H](CCC(O)C)C(N[C@@H](CCCC(F)(F)F)C(C3=NC=CS3)=O)=O)=O)S2)C=C(C=C1)F
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Nader Fotouhi, et al. Proteosome complex inhibitors targeting clpp1p2 protease. WO2025019626A2.

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

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Molecular Weight Molecular Weight

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Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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