COX-2/15-LOX-IN-1
COX-2/15-LOX-IN-1 (Compound 14) is a COX-2 and 15-lipoxygenase enzyme (15-LOX) inhibitor with IC50 values of 10.65, 0.075 and 2.98 μM against COX-1, COX-2 and 15-LOX, respectively. COX-2/15-LOX-IN-1 shows anti-inflammatory activity.
For research use only. We do not sell to patients.
- CAS No.: 2413565-15-6
- Formula: C21H21N7S3
- Molecular Weight:467.63
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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COX-2 0.075 μM (IC50) |
15-LOX 2.98 μM (IC50) |
COX-1 10.65 μM (IC50) |
Chemical Information
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CAS No. 2413565-15-6
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Molecular Weight 467.63
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Formula C21H21N7S3
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SMILES
S=C(NC1=CC=CC=C1)N/N=C(C)/CNC2=NC(N3C(SC)=NC4=CC=CC=C34)=CS2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)