CRBN ligand-777
CRBN ligand-777 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-777 can be linked to a target protein ligand via a linker to form a PROTAC.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- 화학식: C₁₄H₁₁FN₄O₂
- 분자량:286.26
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
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Help & FAQs
Biological Activity
제품 설명
IC50 & Target
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Cereblon |
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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분자량 286.26
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화학식 C₁₄H₁₁FN₄O₂
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SMILES
C#CC1=C(F)C2C(=NN(C)C=2C=C1)N3C(=O)NC(=O)CC3
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CRBN ligand-777 Related Classifications
HY-W999609 Related Classifications
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