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Cat. No.: HY-180351

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CU-6PMN

CU-6PMN is a fluorescent RXR agonist. CU-6PMN has a maximum absorption wavelength of 396 nm and an emission wavelength of 453 nm in 0.1 N NaOH aqueous solution. CU-6PMN has an EC₅₀ value of 22 nM and a K_i value of 230 nM for human RXRα. CU-6PMN can be used in research related to the screening of RXR ligands.

For research use only. We do not sell to patients.

CAS No.: 2099034-38-3
Formula: C₂₅H₂₆O₅
Molecular Weight:406.48

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

CU-6PMN Chemical Structure

CAS No.: 2099034-38-3

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

All RAR/RXR Isoforms :

Chemical Information

CAS No. 2099034-38-3
Molecular Weight 406.48
Formula C₂₅H₂₆O₅
SMILES

O=C(O)C1=CC2=CC(=C(O)C=C2OC1=O)C3=CC4=C(C=C3C)C(C)(C)CCC4(C)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Yamada S, et al. Competitive Binding Assay with an Umbelliferone-Based Fluorescent Rexinoid for Retinoid X Receptor Ligand Screening. J Med Chem. 2019 Oct 10;62(19):8809-8818. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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