Cucurbitacin A
Cucurbitacin A, a triterpenoid that could be isolated from the Stems of Cucumis melo, shows anti-cancer activity.
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- CAS No.: 6040-19-3
- 화학식: C32H46O9
- 분자량:574.70
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
0.4 μM
Compound: 11
|
Cytotoxicity against human A549 cells after 72 hrs by SRB assay
Cytotoxicity against human A549 cells after 72 hrs by SRB assay
|
[PMID: 19348465] |
| Bel-7402 | IC50 |
0.3 μM
Compound: 11
|
Cytotoxicity against human Bel7402 cells after 72 hrs by SRB assay
Cytotoxicity against human Bel7402 cells after 72 hrs by SRB assay
|
[PMID: 19348465] |
| CHO | IC50 |
55.2 μM
Compound: 4
|
Cytotoxicity against CHO cells by MTT assay
Cytotoxicity against CHO cells by MTT assay
|
[PMID: 30108825] |
Cucurbitacin A inhibits the proliferation of A549 and BEL-7402 cells with IC50 values of 0.4 and 0.3 μM, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 6040-19-3
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분자량 574.70
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화학식 C32H46O9
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SMILES
OC[C@]12[C@](CC=C3[C@@]2([H])C[C@@H](C(C3(C)C)=O)O)([H])[C@]4([C@](CC1=O)([C@@]([C@@H](C4)O)([H])[C@@](C)(O)C(/C=C/C(C)(C)OC(C)=O)=O)C)C
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Structure Classification
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Initial Source
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)