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Cytochalasin E 

Cat. No.: HY-N6772
Handling Instructions

Cytochalasin E, an epoxide containing Aspergillus-derived fungal metabolite, inhibits angiogenesis and tumor growth. Cytochalasin E is a potent actin depolymerization agent, and it binds and caps the barbed end of actin filaments to prevent actin elongation.

For research use only. We do not sell to patients.

Cytochalasin E Chemical Structure

Cytochalasin E Chemical Structure

CAS No. : 36011-19-5

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Description

Cytochalasin E, an epoxide containing Aspergillus-derived fungal metabolite, inhibits angiogenesis and tumor growth. Cytochalasin E is a potent actin depolymerization agent, and it binds and caps the barbed end of actin filaments to prevent actin elongation[1][2].

In Vitro

Cytochalasin E prominently inhibits the growth of A549 cells in a dose-dependent manner[3].
Cytochalasin E could induce the up-regulation of autophagy-related protein (LC3-II) and SQSTM1/p62[3].

Molecular Weight

495.56

Formula

C₂₈H₃₃NO₇

CAS No.

36011-19-5

SMILES

O=C1[[email protected]]2(O3)[C@]([[email protected]@H]([[email protected]](O4)(C)[[email protected]@H]4[[email protected]]2([H])/C=C/C[[email protected]@H](C([[email protected]](C)(O)/C=C/OC3=O)=O)C)C)([H])[[email protected]](CC5=CC=CC=C5)N1

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Room temperature in continental US; may vary elsewhere

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Cytochalasin E
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