D-Ribose-d-1
D-Ribose-d-1 is the deuterium labeled D-Ribose. D-Ribose is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose is active in protein g
For research use only. We do not sell to patients.
- CAS No.: 202480-69-1
- Formula: C5H9DO5
- Molecular Weight:151.14
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 202480-69-1
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Unlabeled Cas 50-69-1
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Molecular Weight 151.14
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Formula C5H9DO5
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SMILES
O=C[C@]([C@@H]([C@@H](CO)O)O)([2H])O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
H2O : 100 mg/mL (661.64 mM; Need ultrasonic and warming)
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Hong J, et al. D-ribose induces nephropathy through RAGE-dependent NF-κB inflammation. Arch Pharm Res. 2018 Aug;41(8):838-847. [Content Brief]
Complete Stock Solution Preparation Table
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 6.6164 mL | 33.0819 mL | 66.1638 mL | 165.4096 mL |
| 5 mM | 1.3233 mL | 6.6164 mL | 13.2328 mL | 33.0819 mL | |
| 10 mM | 0.6616 mL | 3.3082 mL | 6.6164 mL | 16.5410 mL | |
| 15 mM | 0.4411 mL | 2.2055 mL | 4.4109 mL | 11.0273 mL | |
| 20 mM | 0.3308 mL | 1.6541 mL | 3.3082 mL | 8.2705 mL | |
| 25 mM | 0.2647 mL | 1.3233 mL | 2.6466 mL | 6.6164 mL | |
| 30 mM | 0.2205 mL | 1.1027 mL | 2.2055 mL | 5.5137 mL | |
| 40 mM | 0.1654 mL | 0.8270 mL | 1.6541 mL | 4.1352 mL | |
| 50 mM | 0.1323 mL | 0.6616 mL | 1.3233 mL | 3.3082 mL | |
| 60 mM | 0.1103 mL | 0.5514 mL | 1.1027 mL | 2.7568 mL | |
| 80 mM | 0.0827 mL | 0.4135 mL | 0.8270 mL | 2.0676 mL | |
| 100 mM | 0.0662 mL | 0.3308 mL | 0.6616 mL | 1.6541 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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