DAGLβ-IN-1
Based on 1 Customer Validation
DAGLβ-IN-1 is an inhibitor of diacylglycerol lipase-β (DAGLβ), serves as a versatile intermediate for the design of DAGL-tailored activity-based probes.
For research use only. We do not sell to patients.
- Purity: 98.22%
- CAS No.: 1402612-61-6
- Formula: C28H34F3N5O4
- Molecular Weight:561.60
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Storage:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
DAGLβ[1]
Diacylglycerol lipase-β (DAGLβ) is a principal biosynthetic enzyme for the endocannabinoid 2-arachidonoylglycerol (2-AG)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1402612-61-6
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Appearance Oil
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Molecular Weight 561.60
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Formula C28H34F3N5O4
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Color Off-white to light yellow
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SMILES
O=C(N1N=NC(C2=CC=C(OC(F)(F)F)C=C2)=C1)N(CCC3=CC=CC=C3)CCCCCNC(OC(C)(C)C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (267 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Ku-Lung Hsu, et al. Development and Optimization of Piperidyl-1,2,3-Triazole Ureas as Selective Chemical Probes of Endocannabinoid Biosynthesis. J Med Chem . 2013 Nov 14;56(21):8257-69. [Content Brief]
[2]. Tiziana Bisogno, et al. Cloning of the First sn1-DAG Lipases Points to the Spatial and Temporal Regulation of Endocannabinoid Signaling in the Brain. J Cell Biol. 2003 Nov 10;163(3):463-8. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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