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Cat. No.: HY-176849

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DDR2-IN-2

DDR2-IN-2 is a Discoidin domain receptor 2 (DDR2) inhibitor. DDR2-IN-2 can be used for the research of cancer.

For research use only. We do not sell to patients.

CAS No.: 3038810-93-1
Formula: C₂₄H₂₅F₄N₅O₂
Molecular Weight:491.48

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

DDR2-IN-2 Chemical Structure

CAS No.: 3038810-93-1

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

DDR2-IN-2 is a Discoidin domain receptor 2 (DDR2) inhibitor. DDR2-IN-2 can be used for the research of cancer^[1].

IC₅₀ & Target^[1]

DDR2

All Discoidin Domain Receptor Isoforms :

DDR1
DDR2

In Vitro

DDR2-IN-2 (Compound 7t) (1.0 μM) shows weak inhibition observed against DDR2 (26%)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 3038810-93-1
Molecular Weight 491.48
Formula C₂₄H₂₅F₄N₅O₂
SMILES

O=C(NCC1=CN(CC(N2CCN(CC2)C)=O)C3=C1C=C(F)C=C3)NC4=CC=C(C(F)(F)F)C=C4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Liu S, et al. Design, synthesis, and biological evaluation of novel discoidin domain receptor inhibitors for the treatment of lung adenocarcinoma and pulmonary fibrosis. Eur J Med Chem. 2024;265:116100. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References

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DDR2-IN-2

All Discoidin Domain Receptor Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

DDR2-IN-2 Related Classifications

HY-176849 Related Classifications