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Art. -Nr.: HY-49373

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AChE-IN-64

AChE-IN-64 (compound C4) is an AChE inhibitor (IC₅₀: 36.9 µM), and can be used for cognitive disorders research.

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CAS. Nr.: 148305-62-8
Formel: C₁₅H₁₁BrO₂
Molecular Weight:303.15

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

AChE-IN-64 Chemical Structure

CAS. Nr.: 148305-62-8

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

AChE-IN-64 (compound C4) is an AChE inhibitor (IC₅₀: 36.9 µM), and can be used for cognitive disorders research^[1].

IC₅₀ & Target^[1]

AChE

36.9 μM (IC₅₀)

Alle Cholinesterase (ChE) Isoform-spezifische Produkte anzeigen :

AChE
BChE

Cellular Effect

Cell Line	Type	Value	Description	References
CCRF-CEM	IC₅₀	12.8 μM Compound: 34	Concentration required to inhibit 50% growth of Human CEM T-lymphocytes cells Concentration required to inhibit 50% growth of Human CEM T-lymphocytes cells	[PMID: 9544201]
L1210	IC₅₀	29.4 μM Compound: 34	Concentration required to inhibit 50% growth of L1210 leukemia cells Concentration required to inhibit 50% growth of L1210 leukemia cells	[PMID: 9544201]
P388	IC₅₀	12.9 μM Compound: 34	Inhibition of proliferation of murine P388 cells Inhibition of proliferation of murine P388 cells	[PMID: 9544201]

Chemical Information

CAS. Nr. 148305-62-8
Molecular Weight 303.15
Formel C₁₅H₁₁BrO₂
SMILES

O=C(C1=CC=C(Br)C=C1)/C=C/C2=CC=C(O)C=C2
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Malik YA, et al. Chalcone Scaffolds Exhibiting Acetylcholinesterase Enzyme Inhibition: Mechanistic and Computational Investigations. Molecules. 2022 May 16;27(10):3181. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
Chemical Information
Reinheit & Dokumentation
Verweise

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AChE-IN-64

Alle Cholinesterase (ChE) Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

AChE-IN-64 Related Classifications

HY-49373 Related Classifications