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Art. -Nr.: HY-D3182

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AldRed 588-A

AldeRed 588-A is a fluorescent labeling reagent and a substrate for aldehyde dehydrogenase (ALDH). AldeRed 588-A is metabolized by functionally active ALDH enzymes, thereby specifically labeling viable ALDH^bright cell populations with red-shifted fluorescence. AldeRed 588-A supports one-step isolation and sorting of ALDH-expressing cells (including normal stem cells and cancer stem cells), and can be used in combination with green fluorophores for multicolor experimental applications. AldeRed 588-A is widely applicable to research related to various cancers such as bladder cancer, breast cancer, and head and neck cancer.

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CAS. Nr.: 2252329-12-5
Formel: C₁₈H₁₇BF₂N₄O₂
Molecular Weight:370.16

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

AldRed 588-A Chemical Structure

CAS. Nr.: 2252329-12-5

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
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- In Vitro
Chemical Information
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Bioz

Biologische Aktivität

Beschreibung

Alle Aldehyde Dehydrogenase (ALDH) Isoform-spezifische Produkte anzeigen :

In Vitro

AldRed 588-A identifies ALDH^bright cell populations in cell lines expressing functional ALDH with potency comparable to that of ALDEFLUOR^TM, and enables one-step isolation of ALDH-expressing cells when co-incubated with ALDEFLUOR^TM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 2252329-12-5
Molecular Weight 370.16
Formel C₁₈H₁₇BF₂N₄O₂
SMILES

O=CCNC(CCC1=[N]2[B+3]([F-])([F-])[N-]3C(C4=CC=CN4)=CC=C3C=C2C=C1)=O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Dollé L, et al. Next generation of ALDH substrates and their potential to study maturational lineage biology in stem and progenitor cells. Am J Physiol Gastrointest Liver Physiol. 2015;308(7):G573-G578. [Content Brief]

[2]. Asbrock N, et al. A red-shifted fluorescent substrate for aldehyde dehydrogenase, AldeRed 588-A, for labeling viable ALDH-positive cells[J]. Cancer Research, 2016, 76(14_Supplement): 2508-2508.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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AldRed 588-A

Alle Aldehyde Dehydrogenase (ALDH) Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

AldRed 588-A Related Classifications

HY-D3182 Related Classifications