CP320626
CP320626 is a potent inhibitor of human liver glycogen phosphorylase (IC50=205 nM). CP320626 reduces blood glucose in diabetic mice without changing plasma insulin levels. CP320626 can be used in the study of type 2 diabetes.
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- CAS. Nr.: 186430-23-9
- Formel: C23H23ClFN3O3
- Molecular Weight:443.90
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Hepatocyte | IC50 |
1.7 μM
Compound: CP-320626
|
Inhibition of glucagon-induced glycogenolysis in Sprague-Dawley rat hepatocytes
Inhibition of glucagon-induced glycogenolysis in Sprague-Dawley rat hepatocytes
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[PMID: 18434170] |
| Hepatocyte | IC50 |
1.7 μM
Compound: CP-320626
|
Inhibition of glucagon-induced glucose output in cultured rat primary hepatocytes
Inhibition of glucagon-induced glucose output in cultured rat primary hepatocytes
|
[PMID: 18952447] |
Chemical Information
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CAS. Nr. 186430-23-9
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Molecular Weight 443.90
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Formel C23H23ClFN3O3
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SMILES
O=C(C(N1)=CC2=C1C=CC(Cl)=C2)N[C@@H](CC3=CC=C(F)C=C3)C(N4CCC(O)CC4)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)