Ganodermic acid S
Ganodermic acid S is an oxygenated triterpenoid, that can be isolated from the Chinese medicinal fungus Ganoderma lucidum (Fr.) Karst (Polyporaceae). Ganodermic acid S exerts a concentration dependent inhibition on the response of human gel-filtered platelets (GFP) to U-46619 (HY-108566), a thromboxane (TX) A2 mimetic.
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- CAS. Nr.: 112430-63-4
- Formel: C34H50O6
- Molecular Weight:554.76
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Vero | IC50 |
32 μM
Compound: 35
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Cytotoxicity against African green monkey Vero cells by GFP based microplate assay
Cytotoxicity against African green monkey Vero cells by GFP based microplate assay
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[PMID: 28504879] |
Ganodermic acid S inhibits U46619-activated platelet aggregation. Ganodermic acid S strongly inhibits U46619-induced diacylglycerol formation, Ca2+ mobilization, granule secretion, and arachidonic acid release[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 112430-63-4
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Molecular Weight 554.76
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Formel C34H50O6
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SMILES
CC1([C@H](CC[C@@]2(C3=CC[C@@]4([C@H](C[C@@H]([C@]4(C3=CC[C@@]12[H])C)OC(C)=O)[C@@H](CC/C=C(C(O)=O)\C)C)C)C)OC(C)=O)C
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Structure Classification
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Initial Source
Ganoderma lucidum
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)