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Art. -Nr.: HY-110166R

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PD 90780 (Standard)

PD 90780 (Standard) is the analytical standard of PD 90780 (HY-110166). This product is intended for research and analytical applications. PD 90780 is a non peptide antagonist of nerve growth factor (NGF). PD 90780 interacts with NGF, prevents NGF binds with p75NTR. PD 90780 inhibits NGF-p75NTR interaction with IC₅₀s of 23.1 and 1.8 μM in PC12 cells and PC12nnr5 cells, respectively .

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CAS. Nr.: 77422-99-2
Formel: C₁₉H₁₄N₄O₄
Molecular Weight:362.34

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

PD 90780 (Standard) Chemical Structure

CAS. Nr.: 77422-99-2

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Product Information
- Information
- Anwendung
Chemical Information
Reinheit & Dokumentation
Calculators
Help & FAQs
Classifications
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Product Information

Information

Anwendung

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS. Nr. 77422-99-2
Molecular Weight 362.34
Formel C₁₉H₁₄N₄O₄
SMILES

CN1C2=CC(C(O)=O)=NN2C(C3=CC(NC(C4=CC=CC=C4)=O)=CC=C13)=O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Verweise

[1]. Colquhoun A , et al. Differential activity of the nerve growth factor (NGF) antagonist PD90780 [7-(benzolylamino)-4,9-dihydro-4-methyl-9-oxo-pyrazolo[5,1-b]quinazoline-2-carboxylic acid] suggests altered NGF-p75NTR interactions in the presence of TrkA. J Pharmacol Exp Ther. 2004 Aug;310(2):505-11. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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